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D2 GCSE Mathematics Past Paper Paper 2 November 1998. Paper 1 November 1998 [Citation needed] Edit. May. 2017. In: D2 GCSE Mathematics Past Papers (1998).
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Paper 1 November 1998. Students usually work in groups of four with one member of the group acting as the note taker. Read our ib physics past papers november 1998 mynms utilities manual of Britain: Powering the future with our energyMalignant melanoma with an unknown primary: prognosis and therapeutic options.
The term "malignant melanoma with an unknown primary" describes patients whose melanoma has metastasized but the tumor's origin has not been identified. We analyzed our experience with such patients in an attempt to determine prognostic factors and appropriate therapeutic options. We retrospectively reviewed the records of patients with melanoma whose tumors lacked a definite primary site. Fifty-seven patients were identified, including 11 with distant metastasis. The main presenting symptom was a palpable lymph node in 36 (63%) patients. The majority of lesions (58%) were amelanotic, and the ulcerated type was seen in 33 patients (58%). A sentinel lymph node biopsy was performed in 43 (75%) patients. In the remaining patients, either no axillary lymph node was found (5 [9%] patients) or axillary lymph node biopsy was performed but no sentinel node was identified (14 [25%] patients). Most patients had received prior immunotherapy (63%), surgery (54%), or both (29%). Surgical intervention consisted of nodal excision (32%) and metastatectomy (17%). Fifteen patients received adjuvant immunotherapy. The median time to recurrence was 5.5 months (range, 0 to 39 months), and the median survival was 29 months. By multivariate analysis, sentinel node status (node-positive be359ba680
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